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Nutrition9. März 2026 · 7 min

Protein quality instead of protein quantity — why lysine decides the ration

Not how much protein counts, but which. Limiting amino acids, biological value and the typical gaps of a pure grass ration — soberly classified.

ER

Equiterna Redaktion

Equine nutritionist · NRC / GfE

Article image: Protein quality instead of protein quantity — why lysine decides the ration

About protein one usually speaks in quantities in the horse: crude protein, per cent in the ration, grams per day. That falls short. A protein is only as valuable as its scarcest building block — and in the horse this scarcest building block is almost always a particular amino acid. The quality of the protein decides, not its mass alone.

The principle of the limiting amino acid

The body builds protein according to a fixed blueprint — if a single essential amino acid is missing, the whole synthesis stalls, no matter how abundantly the others are present. This scarcest amino acid is called the first-limiting one. In the typical horse ration of grass, hay and grain this is lysine. Once it is used up, the remaining protein can no longer be fully utilised — the horse excretes the surplus instead of building it in. After lysine follow methionine and threonine in the discussion as second- and third-limiting.

Lysine · maintenance adult
~4,3
g digestible lysine / day per 100 kg BW, maintenance · requirement rises markedly with growth (NRC 2007)

Exactly here the term biological value comes in: it describes how well the amino acid pattern of a feed fits the requirement of the horse. A feed with high crude protein content but unfavourable pattern is worth less than a more sparingly measured one with a balanced profile. It becomes visible where protein is needed: in the musculature, in the regrowing hoof horn and in the coat — all tissues with a high requirement of the matching building blocks.

When it counts particularly — and where the gaps lie

The requirement of high-quality protein is not constant. Growing horses — foals, weanlings, yearlings — have by far the highest relative lysine requirement, because they actively build tissue. In sport with muscle build-up too and in old age, when protein utilisation declines and muscle loss threatens, quality gains weight. A pure pasture or grass ration often does cover the crude protein quantity, but can leave a gap precisely with lysine — especially when the grass is overmature and thinned in its amino acid profile.

“More protein is not better. The right protein is better — and right means in the horse first of all: enough lysine.”
From ration consultation

The research thereby urges differentiation. A controlled study in yearlings found with staggered lysine intake no linear rise in whole-body protein synthesis — a hint that more of a single building block does not automatically translate into more build-up. Amino acids act in interplay, and to supplement beyond the requirement brings no additional benefit. The lesson from this is not less lysine, but to close the gap in a targeted way instead of blindly topping up.

Practice: before an amino acid complementary feed is fed permanently, the look at the total ration is worthwhile — ideally with a hay analysis. If a lysine gap is present by calculation (often in growth, build-up and old age), its targeted balancing is the effective lever; a blanket high dosing beyond the requirement is not. A ration review classifies this.

Protein quality is thus no academic detail but the actual adjusting screw. Whoever knows the first-limiting amino acid and aligns the ration to it feeds more precisely and often more sparingly than whoever looks only at the crude protein value. With protein the rule is: first the pattern, then the quantity.

Sources

PMID:27687933Mastellar et al. 2016, Vet J — Lysine & whole-body protein synthesis in yearlings
NRC 2007NRC — Nutrient Requirements of Horses (lysine / amino acids)
GfE 2014GfE — Recommendations for the energy and nutrient supply of horses (digestible crude protein)

Compounds in this article

Usage note

This content is for information and education. It does not replace veterinary diagnosis or treatment. If your horse shows signs of illness, consult a veterinarian.

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