Joint / GAG

MSM

Methylsulfonylmethane

Mechanism

Methylsulfonylmethan ist eine bioverfügbare organische Schwefelverbindung. Schwefel ist Baustein von Glykosaminoglykanen und Keratin. Die equine Studienlage zu funktionellen Endpunkten ist begrenzt und heterogen.

Cautions

· Quality/purity varies by manufacturer

Sources

JEVS 2016MSM supplementation in horses (JEVS)

PMID:39858215Barshick et al. 2025 (Animals) — MSM und muskuläre Entzündungs-Genexpression nach Belastung, Pferd

PMID:31853292Sp et al. 2020 (Exp Ther Med) — MSM gegen Cortisol-Stress in Rennpferd-Muskelzellen

Equiterna Score

61/100

solid

Science4.5/10

Practical experience6/10

Safety8.4/10

Overall score scale

high overall75–100solid55–74limited0–54

How the Equiterna Score is built

The Equiterna Score combines three dimensions into a value of 0-100: science (40%), practical experience (30%) and safety (30%). It is transparently derived from evidence level, attributed sources (PubMed/journals), legal classification and cautions. The FEI doping status is shown separately as a competition-law note and does not enter the score. Commissions and vendor relationships have no influence on the score. In addition, the editorial safety rating caps the result: it limits the safety dimension and the overall tier (orange: at most solid). For entries rated red, no score is calculated at all. The rating never raises anything — a green rating does not lift a calculated value.

An editorial assessment of the evidence and safety situation — not a healing claim and not an individual recommendation. It does not replace veterinary advice.

Dosageapprox. 8–10 g/animal/day (warmblood)

AMG statusComplementary feed

FEI statusNot listed

SafetyVery safe

Evidenceemerging

Knowledge connections

Related conditions

Osteoarthritis (OA) →organic sulphur source, discussed as antioxidant

Weak Hoof Horn (brittle horn) →organic sulphur source

Bone Spavin (Osteoarthritis of the Tarsal Joints) →organic sulphur source, discussed as antioxidant

Tendon & Ligament Injury (Tendinitis / Desmitis) →organic sulphur source for connective-tissue metabolism (adjunctive)

Hoof Abscess →organic sulphur source for horn metabolism (adjunctive)

Thrush →organic sulphur source for horn metabolism (adjunctive)

Kissing Spines (Overriding Dorsal Spinous Processes / ORDSP) →organic sulphur source, discussed as antioxidant (adjunctive)

Navicular Syndrome (Podotrochlosis) →organic sulphur source, discussed as antioxidant (adjunctive)

Journal articles on this compound

Gelenkstoffwechsel im Alter — was die Wirkstoffe wirklich leisten →

All sources in the study library →

Frequently asked questions

Is MSM a feed or a veterinary medicine for horses?

Equiterna classes MSM as “Complementary feed”. Legal framework: Regulation (EU) 2019/6 / TAMG (DE/AT), Feed Regulation (EC) 767/2009.

Is MSM allowed at FEI competitions?

In the profile, MSM is listed with the FEI status “Not listed”. The current FEI list is authoritative, so please check its latest version.

Which dosage do the sources give for MSM?

Stated in the profile: approx. 8–10 g/animal/day (warmblood). This is information from the literature, not an instruction for an individual horse.

Which sources are there for MSM?

The profile cites: JEVS 2016, PMID:39858215, and PMID:31853292.

Usage note

This content is for information and education. It does not replace veterinary diagnosis or treatment. If your horse shows signs of illness, consult a veterinarian.

“Nothing forced can ever be beautiful.”

Xenophon · On Horsemanship (c. 365 BC)

Equiterna is an intermediary platform for equine knowledge, marketplace and tools — not a veterinary-medicines dealer, veterinary practice or pharmacy. Compound information is source-attributed (PubMed, specialist journals, NRC/GfE, EU regulations) and free of healing claims. Legal framework: Regulation (EU) 2019/6 / TAMG (DE/AT), Feed Regulation (EC) 767/2009, FEI Prohibited Substances List, HWG.

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