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Phytotherapy

Grape seed

Vitis vinifera · OPC

Mechanism

Standardised grape-seed extract provides oligomeric proanthocyanidins (OPC), condensed flavan-3-ol compounds with pronounced in-vitro radical-scavenging/antioxidant activity. From this the traditional application to support the oxidative balance is derived; controlled equine studies on clinical endpoints are, however, lacking. Important for differentiation: what is meant is the standardised grape-seed extract — NOT grapes or raisins. Whole grapes/raisins are discussed separately in the horse as unclear with regard to safety (kidney concerns from other species) and are to be distinguished from the pure seed extract.

Cautions

  • · Use only standardised grape-seed extract — no grapes or raisins
  • · Do not clinically over-buffer the antioxidant status; sensible integration into the overall ration
  • · With double supply of other antioxidants (vitamin E/selenium) keep maximum amounts in view

Sources

PMID:10962138Bagchi et al. 2000 (Toxicology) — Traubenkern-Proanthocyanidine, Radikalfänger/Antioxidans
PMID:28928504Yang et al. 2017 (Molecules) — Bioaktivitätsbasiertes Screening antioxidativer Komponenten im Traubenkern-OPC-Extrakt
Futtermittel-VO 767/2009VO (EG) 767/2009 — Deklaration als Ergänzungsfuttermittel

Usage note

This content is for information and education. It does not replace veterinary diagnosis or treatment. If your horse shows signs of illness, consult a veterinarian.

“Nothing forced can ever be beautiful.”
Xenophon · On Horsemanship (c. 365 BC)

Equiterna is an intermediary platform for equine knowledge, marketplace and tools — not a veterinary-medicines dealer, veterinary practice or pharmacy. Compound information is study-attributed and free of healing claims. Legal framework: Regulation (EU) 2019/6 / TAMG (DE/AT), Feed Regulation (EC) 767/2009, FEI Prohibited Substances List, HWG.