Sulforaphan
Sulforaphane · SFN · 1-Isothiocyanato-4-(methylsulfinyl)butan
Short profile in progress — full depth follows step by step.
Mechanism
Sulforaphan entsteht enzymatisch aus dem Glucosinolat Glucoraphanin (u. a. in Brokkolisprossen). In vitro und im Nagermodell aktiviert es den Keap1-Nrf2-ARE-Signalweg und die Expression von Phase-II-Enzymen (Literaturuebersichten, z. B. Molecular Nutrition & Food Research). Belastbare pharmakokinetische oder klinische Daten beim Pferd liegen nicht vor.
Cautions
- · Datenlage ueberwiegend Human-/Zellmodell
- · Glucosinolat-Quellen (Kreuzbluetler) in grossen Mengen koennen die Schilddruese belasten
Sources
Usage note
This content is for information and education. It does not replace veterinary diagnosis or treatment. If your horse shows signs of illness, consult a veterinarian.
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