Resveratrol

trans-Resveratrol

Mechanism

Resveratrol is a stilbene polyphenol found among others in grapes and Japanese knotweed (Polygonum cuspidatum), showing antioxidant and inflammation-modulating effects in vitro. In the horse it is marketed predominantly in the context of joint comfort and recovery. The oral bioavailability of free resveratrol is low (rapid metabolism to glucuronides/sulfates); micronized formulations are meant to improve absorption. The equine evidence base is limited: in a randomized, placebo-controlled study, sport horses with lameness localized to the distal hock joints received resveratrol as an adjunct after intra-articular triamcinolone injection; lameness was reduced compared to placebo. Meaningful studies on isolated oral administration without concomitant treatment are largely lacking.

Cautions

· Low oral bioavailability — free resveratrol is rapidly metabolized
· Equine data base limited; favorable data mostly from adjunctive settings, not from monotherapy

Sources

PMID:27585103Watts et al. 2016 (JAVMA) — RCT Resveratrol adjuvant bei Sprunggelenks-Lahmheit

PMID:27073333Ownby et al. 2016 (Front Vet Sci) — Resveratrol/Hyaluronsäure bei alten lahmen Pferden, biochemische Parameter

Equiterna Score

59/100

solid

Science4.5/10

Practical experience6/10

Safety7.8/10

Overall score scale

high overall75–100solid55–74limited0–54

How the Equiterna Score is built

The Equiterna Score combines three dimensions into a value of 0-100: science (40%), practical experience (30%) and safety (30%). It is transparently derived from evidence level, attributed sources (PubMed/journals), legal classification and cautions. The FEI doping status is shown separately as a competition-law note and does not enter the score. Commissions and vendor relationships have no influence on the score. In addition, the editorial safety rating caps the result: it limits the safety dimension and the overall tier (orange: at most solid). For entries rated red, no score is calculated at all. The rating never raises anything — a green rating does not lift a calculated value.

An editorial assessment of the evidence and safety situation — not a healing claim and not an individual recommendation. It does not replace veterinary advice.

Dosageproduct-specific (micronized extract); traditionally in the range of ~1,000-3,000 mg/animal/day (large horse), observe manufacturer instructions

AMG statusComplementary feed

FEI statusNot listed

SafetyVery safe

Evidenceemerging

Usage note

This content is for information and education. It does not replace veterinary diagnosis or treatment. If your horse shows signs of illness, consult a veterinarian.

“Nothing forced can ever be beautiful.”

Xenophon · On Horsemanship (c. 365 BC)

Equiterna is an intermediary platform for equine knowledge, marketplace and tools — not a veterinary-medicines dealer, veterinary practice or pharmacy. Compound information is study-attributed and free of healing claims. Legal framework: Regulation (EU) 2019/6 / TAMG (DE/AT), Feed Regulation (EC) 767/2009, FEI Prohibited Substances List, HWG.