Enzyme

Protease

Peptidase · Proteinase · Serin-Protease

Mechanism

Proteasen spalten Nahrungsproteine an Peptidbindungen zu kurzkettigen Peptiden und freien Aminosaeuren. In der Gefluegel- und Schweinefuetterung werden mikrobielle Serin-Proteasen als zootechnische Zusatzstoffe eingesetzt und von der EFSA bewertet (Ronozyme ProAct, serine protease, EFSA-Gutachten pub 6448); Kombipraeparate mit Xylanase und Amylase verbesserten in Broilern die Naehrstoffverdaulichkeit (PMID 27591284). Fuer das Pferd existieren praktisch keine kontrollierten Wirksamkeitsdaten. Das Pferd sezerniert pankreatische Proteasen in den Duenndarm und fermentiert nicht verdautes Protein im Dickdarm; ein Zusatznutzen exogener Proteasen ist damit weder belegt noch physiologisch naheliegend. Evidenz beim Pferd: emerging bzw. unklar.

Cautions

· Keine belastbaren Pferdedaten - Nutzen unbelegt
· Kein Ersatz fuer hochwertige Eiweiss-/Aminosaeurenversorgung
· Zusatzstoff-Deklaration (VO 1831/2003) beachten

Sources

EFSA Journal pub 6448EFSA FEEDAP - Safety and efficacy of serine protease (Ronozyme ProAct) for chickens for fattening

PMID 27591284Effect of exogenous xylanase, amylase and protease on nutrient digestibility and growth performance of broilers fed corn/soy diets, Poult Sci 2016

Equiterna Score

58/100

solid

Science4.5/10

Practical experience6/10

Safety7.2/10

Overall score scale

high overall75–100solid55–74limited0–54

How the Equiterna Score is built

The Equiterna Score combines three dimensions into a value of 0-100: science (40%), practical experience (30%) and safety (30%). It is transparently derived from evidence level, attributed sources (PubMed/journals), legal classification and cautions. The FEI doping status is shown separately as a competition-law note and does not enter the score. Commissions and vendor relationships have no influence on the score. In addition, the editorial safety rating caps the result: it limits the safety dimension and the overall tier (orange: at most solid). For entries rated red, no score is calculated at all. The rating never raises anything — a green rating does not lift a calculated value.

An editorial assessment of the evidence and safety situation — not a healing claim and not an individual recommendation. It does not replace veterinary advice.

DosageKeine etablierte oder validierte Pferde-Dosis. Monogastrier-Rationen dosieren aktivitaetsbezogen (Protease-Einheiten/kg Futter); die Uebertragbarkeit aufs Pferd ist ungeklaert.

AMG statusComplementary feed

FEI statusNot listed

SafetyVery safe

Evidenceemerging

Usage note

This content is for information and education. It does not replace veterinary diagnosis or treatment. If your horse shows signs of illness, consult a veterinarian.

“Nothing forced can ever be beautiful.”

Xenophon · On Horsemanship (c. 365 BC)

Equiterna is an intermediary platform for equine knowledge, marketplace and tools — not a veterinary-medicines dealer, veterinary practice or pharmacy. Compound information is study-attributed and free of healing claims. Legal framework: Regulation (EU) 2019/6 / TAMG (DE/AT), Feed Regulation (EC) 767/2009, FEI Prohibited Substances List, HWG.