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Lavender Foal Syndrome (LFS / CCDL, MYO5A)

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Severe hereditary neurological disease of the newborn Arabian foal (also Coat Color Dilution Lethal), caused by a mutation in the MYO5A gene and inherited autosomal-recessive. Affected foals show the most severe neurological disturbances directly after birth and are not viable; often a diluted (lavender/silvery-pink) coat colour is noticeable at the same time.

Veterinary care required

This condition belongs in veterinary diagnosis and treatment. Compounds are at most supportive.

Priority · vet & management

An affected newborn is to be presented to the vet immediately; LFS is not treatable and not viable, so animal-welfare-appropriate veterinary decisions are in the foreground. For breeding, the carrier gene test of the parent animals is decisive.

Possible causes

  • · autosomal-recessive mutation in the MYO5A gene
  • · only homozygous foals affected; carriers clinically healthy
  • · occurrence especially in Egyptian Arabian lines
  • · disease manifest at birth, not viable

Supportive compounds · supplementary feed, not medication

Prevention

Gene testing of Arabian breeding animals and avoidance of carrier-x-carrier matings prevent affected foals.

Equiterna's take

Equiterna accompanies LFS dignifiedly and factually: at the centre are veterinary support of the newborn and the gene test of the parent animals — no promises of cure, no role for active substances.

Usage note

This content is for information and education. It does not replace veterinary diagnosis or treatment. If your horse shows signs of illness, consult a veterinarian.

Equiterna is an intermediary platform for equine knowledge, marketplace and tools — not a veterinary-medicines dealer, veterinary practice or pharmacy. Compound information is study-attributed and free of healing claims. Legal framework: Regulation (EU) 2019/6 / TAMG (DE/AT), Feed Regulation (EC) 767/2009, FEI Prohibited Substances List, HWG.